Intra-abdominal hemorrhage due to uncontrolled warfarin therapy: Two case reports
Kahya, Mehmet Cemal
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Warfarine is an anticoagulant which acts by inhibiting synthesis of vitamin K-dependent coagulation factor. The most important adverse effect is hemorrhage. Intraabdominal hemorrhage due to anticoagulants is a rare clinical entity and a life threatening complication. Among women in reproductive age receiving long-term warfarine therapy, overian source of hemorrhage is a major cause of intraabdominal hemorrhage and may produce acute abdomen. We present two patients with intraabdominal hemorrhage as a complication of uncontrolled warfarine therapy and treated conservatively.