Evaluation of treatment results of patients treated with splenectomy for idiopathic thrombocytopenic purpura
Yılmaz, Kerim Bora
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Purpose: The treatment results of patients treated with splenectomy for idiopathic thrombocytopenic purpura were evaluated in this study. Patients and Methods: Patients treated with splenectomy for idiopathic trombocytopenic purpura between 1999-2006 were retrospectively evaluated. Patients’ age, gender, preoperative and postoperative medical treatments, duration from the beginning of the treatment to surgery, vaccination status, type of surgical treatment, presence of accessory spleen, and postoperative complications were recorded and early and late postoperative trombocyte responses were evaluated. Results: Five male and eight female patients with a mean age of 38 (14-67) were included in the study. Bleeding was the presenting sign in all patients. Splenectomy was performed since two patients were dependent on and 11 patients were unresponsive to steroid treatment. Two patients had temporary bleeding and hematoma whereas two patients had pneumonia as postoperative complications. Eleven patients (84%) had complete response, one patient (8%) had partial response and one patient (8%) was unresponsive in early postoperative follow-up period. During long-term follow-up, nine patients (69%) had complete response, one patient (8%) had partial response and three patients (23%) were unresponsive to splenectomy. Conclusion: Splenectomy can be performed safely in idiopathic trombocytopenic purpura patients unresponsive to medical treatment to obtain sustained response.