Effect of chemotherapy on quality of life in patients with lymphoma
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Aim: Advances in chemotherapy have significantly prolonged survival of patients with lymphoma and a significant percentage of patients may be cured. The assessment of the quality of life in patients undergoing chemotherapy is of growing interest. The aim of this study is to assess the effect of chemotherapy on quality of life in patients with lymphoma. Methods: All patients (n=49) diagnosed with stage I lymphoma in the Cukurova University Oncology Department from June 2000 to January 2001 received a quality-of-life questionnaire (EORTC QLQ C-30) before chemotherapy and after the second cycle of chemotherapy. Results: Significant improvement during treatment was found in some of the physical activities, emotional functioning, relieve from pain and fatigue, dyspnea, anorexia, sleep, and global quality of life. When chemotherapy, age, gender and lymphoma type were taken into account, the most important factor influencing the global quality of life was educational status. Conclusion: The results may be used to reassure the patients who are reluctant to go through chemotherapy that they are likely to experience an improved quality of life compared to their situation before the treatment.