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dc.contributor.authorJahovic, Nermina
dc.contributor.authorVelioğlu Öğünç, Ayliz
dc.contributor.authorGüzel, Esra
dc.contributor.authorArs, Derya
dc.contributor.authorErcan, Feriha
dc.contributor.authorErkanlı, Gözde
dc.contributor.authorYeğen, Berrak Ç.
dc.contributor.authorYalçın, A. Süha
dc.date.accessioned2014-09-24T17:01:36Z
dc.date.available2014-09-24T17:01:36Z
dc.date.issued2005
dc.identifier.issn1309-9469
dc.identifier.urihttp://hdl.handle.net/11424/3169
dc.description.abstractObjective: Whey is a dietary protein supplement with antioxidant effects. In this study, the protective effects of whey protein against ethanol-induced oxidative gastric injury and associated hepatic injury are evaluated. Methods: Formation of reactive oxygen species in the gastric tissue was monitored, using chemiluminescence technique. Hepatic and gastric tissues were analyzed histologically, while malondialdehyde levels and myeloperoxidase activity of the gastric and hepatic tissues were measured to determine the degree of lipid peroxidation and tissue neutrophil infiltration, respectively. Results: Whey treatment demonstrated protective effects against ethanol-induced gastric and hepatic injury, by inhibiting neutrophil infiltration and generation of cytotoxic free radicals. Conclusion: A nutritional approach with a whey-based product might offer an attractive new choice to support the treatment of gastric lesionsen_US
dc.language.isoenen_US
dc.publisherMarmara Medical Journalen_US
dc.subjectWhey proteins, Ethanol, Gastric and hepatic oxidative damageen_US
dc.titleWhey pretreatment ameliorates gastric and hepatic oxidative damage in ethanol-induced gastric ulcer via a neutrophil-dependent mechanismen_US
dc.typeArticleen_US
dc.contributor.authorIDTR46934en_US
dc.contributor.authorIDTR129034en_US
dc.contributor.authorIDTR6280en_US
dc.contributor.authorIDTR122596en_US


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