Metastatic ductal adenocarcinoma of the prostate: report of a case with fine needle aspiration biopsy findings and histologic Correlation (Olgu Sunumu)
Güllüoğlu, Mine G.
MetadataShow full item record
Prostatic ductal adenocarcinoma is a rare neoplasm that arises from the prostatic urethra and large periurethral prostatic ducts. We described the cytologic features of a cribriform type of prostatic ductal adenocarcinoma in the transthoracic fine needle aspiration material of the pulmonary metastatic lesions in a 74-year-old patient with a previous diagnosis of cribriform type ductal adenocarcinoma in the prostate of which the histologic features were descibed also in the present case report. In the microscopic examination of the aspirate, three-dimentional groups of small cells displaying cribriform features and peripheral palisading cells were observed on a necrotic background. These cells had hyperchromatic round to oval nuclei with clumped chromatin, small inconspicious nucleoli and scant cytoplasm. Positive PSA immunocytochemical staining confirmed the prostatic origin. The present case is the first cribriform type of prostatic ductal adenocarcinoma described with its cytological features. In this case report, we aim to present the cytologic and histologic features of a metastatic prostatic ductal adenocarcinoma with special emphasis on its cytopathological features.