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dc.contributor.authorKERİMOĞLU, Oya
dc.contributor.authorŞAHBAZ, Sevinç
dc.contributor.authorŞEHİRLİ, Ahmet Özer
dc.contributor.authorDORTUNÇ, Betül
dc.contributor.authorŞENER, Göksel
dc.date.accessioned2015-08-24T12:56:59Z
dc.date.available2015-08-24T12:56:59Z
dc.date.issued2015
dc.identifier.urihttp://hdl.handle.net/11424/4009
dc.description.abstractThe objective of this study was to evaluate the mechanical properties of transdermal therapeutic systems (TTS) containing captopril together with synthetic and pH independent polymers, Eudragit RL 100 and RS 100. The formulations were characterized in terms of their adhesiveness and bioadhesiveness by using texture analyser. These optimum formulations were chosen according to the results of our previous study regarding in vitro dissolution and ex vivo diffusion rate studies through excised human skin by using Franz Diffusion Cell. Results indicated that the mechanical properties of the formulations were suitable to be used as a transdermal patch.en_US
dc.language.isoengen_US
dc.subjectcaptopril, transdermal therapeutic system, patch adhesiveness, patch bioadhesiveness, texture analyseren_US
dc.titleMechanical evaluation of matrix type transdermal therapeutic systems containing captoprilen_US
dc.typeArticleen_US
dc.contributor.authorIDTR171992en_US
dc.contributor.authorIDTR173376en_US
dc.contributor.authorIDTR46476en_US
dc.contributor.authorIDTR6213en_US
dc.contributor.authorIDTR7405en_US
dc.relation.journalMarmara Pharmaceutical Journalen_US
dc.identifier.volume19en_US
dc.identifier.issue1en_US
dc.identifier.startpage62en_US
dc.identifier.endpage72en_US


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