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dc.contributor.authorErenus, Mithat
dc.contributor.authorUluğ, Ulun
dc.contributor.authorBaşgül, Alin
dc.date.accessioned2016-04-13T14:28:46Z
dc.date.available2016-04-13T14:28:46Z
dc.date.issued1999
dc.identifier.urihttp://hdl.handle.net/11424/4388
dc.description.abstractObjective: The purpose of this prospective study is to investigate the impact of adding active vitamin D metabolite to hormone replacement therapy (HRT) in the treatment of osteoporosis in early postmenopausal women. Methods: Fifty-two naturally postmenopausal women receiving either 0.625 mg conjugated estrogen with 2.5 mg medroxyprogesterone acetate daily for 12 months or 0.50 pgr one alpha cholecalciferol in addition to 0.625 mg conjugated estrogen with 2.5 mg medroxyprogesterone acetate daily for 12 months. Results: Bone mass density (BMD) increases significantly in both treatment groups at 12 months not only in proximal femur but in the lumbar spine as well. In the HRT + alpha calcidiol group, the percentage of change in BMD for the proximal femur was 17.32 ± 22.41 and 15.02 ± 10.05 for the lumbar spine. In the HRT alone treatment group the percentage of change in BMD was 12.21 ± 12.81 and 9.44 ± 8.01 for the proximal femur and the lumbar spine respectively. Conclusion: Addition of vitamin D metabolite seemed to potentiate the BMD elevating effect of HRT even though the positive trend in the BMD change was not statistically significant in one yearen_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAlpha calcidiol, Bone Density, Hormone Replacement Therapyen_US
dc.titleThe ımpact of vıtamın d3 metabolıte to hormone replacement therapy on bone densıty ın early postmenopausal womenen_US
dc.typearticleen_US
dc.contributor.authorIDTR240935en_US
dc.relation.journalMarmara Medicial Journalen_US
dc.contributor.departmentDepartment of Obstetrics and Gynecology, School of Medicine, Marmara University, istanbul, Turkeyen_US
dc.identifier.volume12en_US
dc.identifier.issue2en_US
dc.identifier.startpage63en_US
dc.identifier.endpage66en_US


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