Effect of alpha-actinin-3 gene on trained and untrained Turkish middle-school childrens sprinting performance: A pilot study
Güney, Ahmet Ilter
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ACTN3 R577X polymorphism was evaluated in trained and untrained Turkish middle-school childrens sprinting performance. Twenty trained and 30 untrained children were genotyped; the frequencies of RR, RX and XX genotypes were 65, 30 and 5% in the trained individuals and 50, 27 and 23% in the controls (untrained), respectively. The R allele was present in 80% of the trained and 63% of the untrained individuals, whereas the X allele was present in 20% of the trained and 37% of the untrained individuals. The average values of time taken for running 50 m for the trained and untrained groups were 10.21 ± 0.68 and 11.88 ± 1.18 s in RR genotypes, and 10.48 ± 0.54 and 12.28 ± 1.26 s in RX genotypes, respectively. These differences were statistically significant and ecologically meaningful. Such polymorphism may form an informative criterion for identifying individuals who might become talented sprinters with suitable training. © 2014 Taylor & Francis.