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dc.contributor.authorBahar, Arif
dc.contributor.authorKarademir, Ferhan
dc.contributor.authorUnsur, Tolga
dc.contributor.authorÖzyurt, Mustafa
dc.contributor.authorGöçmen, İsmail
dc.date.accessioned2016-06-03T08:55:34Z
dc.date.available2016-06-03T08:55:34Z
dc.date.issued2003
dc.identifier.urihttp://hdl.handle.net/11424/4592
dc.description.abstractObjective: In this study we aimed to compare the efficacy and safety of isepamicin versus amikacin at a dose of 7.5 mg/kg of body weight twice daily for 10-14 days in children with urinary tract infections (UTI). Methods: One hundred and seventeen patients with urinary tract infection were enrolled in this study. Patients were randomized to treatment with isepamicin or amikacin in a 1:2 ratio. Urinary tract infections were treated with isepamicin (n=42), or amikacin (n=75). Results: The most commonly isolated pathogens were Escherichia coli, Staphylococcus spp., Klebsiella pneumonia, Proteus mirabilis and Enterobacter spp. The overall clinical response rate at the end of treatment was excellent in all treatment groups (93.0/93.4% cured) with no significant differences between isepamicin and amikacin in patients with infections. None of the patients had a life-threatening or severe adverse event that required discontinuation of the drug. Conclusion: Isepamicin was shown to be as effective and as well tolerated as amikacin in the treatment of urinary tract infections in pediatric patients.en_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIsepamicin, Amikacin, Aminoglycoside, Pediatrics.en_US
dc.titleComparıson of the effıcacy and safety of ısepamıcın and amıkacın ın the treatment of urınary tract ınfectıon ın chıldrenen_US
dc.typearticleen_US
dc.contributor.authorIDTR8922en_US
dc.contributor.authorIDTR105355en_US
dc.contributor.authorIDTR8802en_US
dc.relation.journalMarmara Medical Journalen_US
dc.identifier.volume16en_US
dc.identifier.issue2en_US
dc.identifier.startpage107en_US
dc.identifier.endpage112en_US


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