The effect of prolonged time for achieving ovarian suppression before starting stimulation on pregnancy rates in ART cycles
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Objective: To determine if the prolonged time for achieving ovarian suppression before starting stimulation affected the pregnancy rates. Patients and Methods: Retrospective cohort analysis was performed on 565 women undergoing first assisted reproductive technologies (ART) treatment in a University-affiliated Hospital. The women were grouped according to the duration of downregulation by gonadotropin-releasing hormone (GnRH) analogue. Group A consisted of women in the lower 25th percentile, group B consisted of women in the upper 25th percentile, according to the duration of GnRH analogue use. The implantation and clinical pregnancy rates were compared. Results: Mean number of aspirated and inseminated oocytes were more in group A than in group B. Implantation rates were similar. Clinical pregnancy rates were alike. Conclusion: Prolonged time for achieving ovarian supression does not compromise clinical pregnancy rates in ART cycles.