Non immune hydrops fetalis: two premature infants with favorable outcome
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Non immune hydrops fetalis is defined as the excessive accumulation of fluid in two or more compartments of the fetus in the absence of any maternal-fetal blood incompatibility. The clinical presentations include ascites, scalp edema, pleural or pericardial effusions and polyhydramnios. Perinatal mortality in this severe clinical condition is high, between 50-98%. Prematurity is an important risk factor for mortality. Despite many advances in diagnosis, therapy and ventilation management during the last decade in neonatal intensive care units, the mortality rate has not changed very much for hydropic infants. This is the report of the management of two premature infants born severely hydropic. The first infant had tachyarrhythmia, the second infant had Noonan syndrome. Both infants had a good prognosis.